INT280449

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.79
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Phc1) DNA binding (Phc1)
Phc1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 2 100.00 Very High Very High Very High
Clonidine 16 99.98 Very High Very High Very High
Dopamine 10 97.68 Very High Very High Very High
Central nervous system 2 88.56 High High
cocaine 10 82.80 Quite High
addiction 6 75.96 Quite High
methadone 2 74.20 Quite High
headache 4 72.16 Quite High
transdermal 6 70.80 Quite High
drug abuse 12 55.36 Quite High
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 294 99.96 Very High Very High Very High
Tourette's Syndrome 4 90.24 High High
Sleep Disorders 16 89.60 High High
Aggression 6 89.20 High High
Cocaine Dependence 4 75.96 Quite High
Headache 4 72.16 Quite High
Anxiety 2 68.96 Quite High
Vomiting 4 67.68 Quite High
Syndrome 4 60.64 Quite High
Substance Abuse 34 55.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 10 patients treated with MPH, single photon emission computed tomography (SPECT) imaging demonstrated that MPH lowered striatal DAT availability in adults with ADHD.52
Positive_regulation (with) of Gene_expression (treated) of MPH associated with attention deficit hyperactivity disorder and imagery
1) Confidence 0.05 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2732009 Disease Relevance 0.63 Pain Relevance 0.31
Results indicated no significant benefit of clonidine over MPH as measured by the Connor’s Teachers Abbreviated Symptom Questionnaire.69


Neg (no) Positive_regulation (over) of Gene_expression (over) of MPH associated with clonidine
2) Confidence 0.04 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2732009 Disease Relevance 1.16 Pain Relevance 0.78

General Comments

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