INT280473

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk1) extracellular region (Ntf4) plasma membrane (Ntrk1)
kinase activity (Ntrk1) cytoplasm (Ntrk1)
Ntrk1 (Mus musculus)
Ntf4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 4 100.00 Very High Very High Very High
Central nervous system 5 58.28 Quite High
depression 73 50.00 Quite Low
long-term potentiation 2 28.36 Quite Low
Hippocampus 43 11.88 Low Low
antidepressant 62 5.00 Very Low Very Low Very Low
fluoxetine 18 5.00 Very Low Very Low Very Low
Desipramine 10 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 9 81.60 Quite High
Hyperplasia 1 52.76 Quite High
Depression 95 50.00 Quite Low
Suicidal Behaviour 123 32.64 Quite Low
Mental Disorders 6 29.52 Quite Low
Stress 25 21.88 Low Low
Cognitive Disorder 4 15.32 Low Low
Frailty 1 10.28 Low Low
Urological Neuroanatomy 17 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The interaction of neurotrophins with the Trk receptors is specific: NGF binds with TrkA, BDNF and NT 4 both bind with TrkB, and NT 3 binds with the highest affinity to TrkC but is also capable of signaling through TrkA and TrkB.
Trk Binding (binds) of NT 4 associated with nerve growth factor
1) Confidence 0.00 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2732010 Disease Relevance 0.13 Pain Relevance 0.20

General Comments

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