INT280475

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (Mecp2) embryo development (Mecp2) DNA binding (Mecp2)
protein complex (Mecp2) response to stress (Mecp2) cytoplasm (Mecp2)
Bdnf (Mus musculus)
Mecp2 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 62 88.76 High High
depression 73 88.00 High High
Hippocampus 43 5.00 Very Low Very Low Very Low
fluoxetine 18 5.00 Very Low Very Low Very Low
Desipramine 10 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
Nerve growth factor 4 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
amygdala 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 95 93.76 High High
Suicidal Behaviour 123 85.24 High High
Repression 2 71.20 Quite High
Injury 1 63.20 Quite High
Cognitive Disorder 4 61.20 Quite High
Stress 25 52.56 Quite High
Urological Neuroanatomy 17 5.00 Very Low Very Low Very Low
Congenital Anomalies 9 5.00 Very Low Very Low Very Low
Mental Disorders 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Methyl-CpG binding protein MeCP2, which encodes a protein that functions as a transcriptional repressor, selectively binds to BDNF promoter III and represses expression of the Bdnf gene.
BDNF Binding (binds) of MeCP2
1) Confidence 0.11 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2732010 Disease Relevance 0.92 Pain Relevance 0.22

General Comments

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