INT28055

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Context Info
Confidence 0.03
First Reported 1989
Last Reported 1995
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.30
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
gonadal 1
Ces2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 4 100.00 Very High Very High Very High
Bile 1 100.00 Very High Very High Very High
Morphine 1 94.88 High High
headache 1 90.52 High High
withdrawal 2 84.20 Quite High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 1 99.22 Very High Very High Very High
Hyponatremia 1 98.48 Very High Very High Very High
Duodenal Ulcer 1 97.84 Very High Very High Very High
Nicotine Addiction 1 95.00 High High
Headache 1 90.52 High High
Appetite Loss 1 90.12 High High
Vomiting 2 89.60 High High
Eosinophilia 1 88.48 High High
Chills 1 88.28 High High
Fever 1 87.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two sulfotransferase isoenzyme activities (acetaminophen sulfotransferase 2 and bile salt sulfotransferase I) previously shown to be regulated by gonadal hormones were also unchanged.
Neg (unchanged) Positive_regulation (unchanged) of sulfotransferase isoenzyme in gonadal associated with bile and paracetamol
1) Confidence 0.03 Published 1989 Journal Dev Pharmacol Ther Section Abstract Doc Link 2714162 Disease Relevance 0 Pain Relevance 0.49
Duodenal ulcers occurred in one patient and one patient had grade 4 cardiac toxicity consisting of an asymptomatic minimal elevation of the creatinine phosphokinase MB isoenzyme (CPK-MB).
Positive_regulation (elevation) of creatinine phosphokinase MB isoenzyme associated with cv unclassified under development and duodenal ulcer
2) Confidence 0.00 Published 1995 Journal Clin. Cancer Res. Section Abstract Doc Link 9815906 Disease Relevance 1.30 Pain Relevance 0.16

General Comments

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