INT280568

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (MRAS, RAF1) plasma membrane (MRAS, RAF1) mitochondrion (RAF1)
GTPase activity (MRAS) cytoplasm (RAF1) cell proliferation (RAF1)
MRAS (Homo sapiens)
RAF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 15 45.20 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
adenocard 5 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Antihistamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 5 91.84 High High
Adenocarcinoma 1 86.20 High High
Cancer 27 82.24 Quite High
Toxicity 7 77.72 Quite High
Disease 33 74.80 Quite High
Malignant Neoplastic Disease 1 61.12 Quite High
Death 1 56.92 Quite High
Hyperplasia 2 55.60 Quite High
Colon Cancer 2 41.16 Quite Low
Non-small-cell Lung Cancer 4 31.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most notably, raf-1 plays a central role in the mitogen activated protein kinase (MAPK) pathway and is activated by ras protein [87].
ras protein Positive_regulation (activated) of raf-1
1) Confidence 0.01 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733095 Disease Relevance 0.70 Pain Relevance 0

General Comments

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