INT280619

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ins1, Srebf1) aging (Srebf1) Golgi apparatus (Srebf1)
endoplasmic reticulum (Srebf1) DNA binding (Srebf1) carbohydrate metabolic process (Ins1)
Anatomy Link Frequency
skeletal muscle 1
Ins1 (Rattus norvegicus)
Srebf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 24 27.16 Quite Low
dexamethasone 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 5 77.80 Quite High
Insulin Resistance 20 77.28 Quite High
Metabolic Syndrome 2 16.32 Low Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Exsanguination 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Obesity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SREBP-1c is transcriptionally induced by insulin and its enhanced expression mediates the transcriptional effects of insulin in skeletal muscle (Guillet-Deniau et al. 2002).
insulin Positive_regulation (induced) of SREBP-1c in skeletal muscle
1) Confidence 0.04 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733097 Disease Relevance 0.16 Pain Relevance 0

General Comments

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