INT28065

Context Info Confidence 0.04 First Reported 1989 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.53 Pain Relevance 0.53

transferase activity, transferring glycosyl groups (fut10) Golgi apparatus (fut10)

fut10 (Rattus norvegicus)

Pain Link Frequency Relevance Heat tetrodotoxin 3 100.00 antagonist 2 89.64 Inflammation 2 72.48 cINOD 1 67.96 Neurotransmitter 1 58.24

Disease Link Frequency Relevance Heat Nephritis 1 93.40 Renal Disease 3 83.36 Injury 1 75.00 INFLAMMATION 3 72.48

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Tx gamma (50 ng) and fraction T2III1 (2.5 ng) produced a tetrodotoxin-sensitive increase in the frequency of miniature endplate potentials (m.e.p.p.) and a transitory reduction of the resting potential.

Negative_regulation (reduction) of Gene_expression (produced) of Tx gamma associated with tetrodotoxin

1) Confidence 0.04 Published 1989 Journal Gen. Pharmacol. Section Abstract Doc Link 2714618 Disease Relevance 0 Pain Relevance 0.31

Dazmegrel, in doses sufficient to effectively block glomerular TxA2 synthesis, significantly increased 12-HETE and PGE2 synthesis without an effect on the synthesis of LTB4.

Negative_regulation (block) of Gene_expression (synthesis) of TxA2

2) Confidence 0.01 Published 1999 Journal J. Lab. Clin. Med. Section Abstract Doc Link 10560941 Disease Relevance 0.53 Pain Relevance 0.22

General Comments

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