INT280651

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.12
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Mpl) molecular_function (Mpl) cellular_component (Mpl)
biological_process (Mpl)
Mpl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 107 77.92 Quite High
dexamethasone 15 7.00 Low Low
Inflammation 10 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 62 66.04 Quite High
Diabetes Mellitus 17 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Exsanguination 8 5.00 Very Low Very Low Very Low
Metabolic Syndrome 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Frailty 6 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The equations describing SREBP-1c mRNA (SREBPm) time profile following MPL treatment are:
MPL Binding (treatment) of
1) Confidence 0.17 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733097 Disease Relevance 0 Pain Relevance 0
The equations describing ET-1 mRNA (mRNA) time profile following MPL treatment are:
MPL Binding (treatment) of
2) Confidence 0.17 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733097 Disease Relevance 0 Pain Relevance 0
The model was developed using the assumption that unbound MPL molecules diffuse through cell membranes and bind with cytosolic free receptors.
MPL Binding (bind) of
3) Confidence 0.16 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733097 Disease Relevance 0.12 Pain Relevance 0.04
The present model was developed using the assumption that being moderately lipophilic, unbound MPL diffuses through cell membranes and binds with cytosolic free glucocorticoid receptors (GR).
MPL Binding (unbound) of
4) Confidence 0.15 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.04

General Comments

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