INT28066

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Context Info
Confidence 0.10
First Reported 1988
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.01
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (fut10) Golgi apparatus (fut10)
Anatomy Link Frequency
diaphragm 1
brainstem 1
mesangial cells 1
fut10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Brush evoked pain 5 99.72 Very High Very High Very High
medulla 2 99.20 Very High Very High Very High
antagonist 2 97.92 Very High Very High Very High
Inflammation 2 85.96 High High
cINOD 1 81.44 Quite High
allodynia 3 77.52 Quite High
intrathecal 1 67.92 Quite High
tetrodotoxin 3 63.68 Quite High
Spinal cord 1 59.04 Quite High
anesthesia 1 46.16 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 8 99.72 Very High Very High Very High
Injury 4 99.62 Very High Very High Very High
Convulsion 4 99.36 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 97.08 Very High Very High Very High
Renal Disease 3 96.84 Very High Very High Very High
Brain Injury 4 95.68 Very High Very High Very High
Nephritis 1 94.12 High High
INFLAMMATION 3 85.96 High High
Peripheral Arterial Disease 1 68.88 Quite High
Decapitation 1 65.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This decrease in PG levels at 15 min was not observed in the rats that had seizures after injury and both PGE2 and TxB2 levels remained high in hemispheres and brainstem.
Regulation (high) of TxB2 in brainstem associated with medulla, convulsion and injury
1) Confidence 0.10 Published 1988 Journal J. Neurotrauma Section Abstract Doc Link 3249309 Disease Relevance 0.76 Pain Relevance 0.09
We investigated the effect of the prosaposin-derived peptide prosaptide TX14(A) on tactile allodynia in rats following intraplantar injection of the HIV envelope glycoprotein gp120.
Spec (investigated) Regulation (effect) of TX14 associated with brush evoked pain and acquired immune deficiency syndrome or hiv infection
2) Confidence 0.08 Published 2008 Journal Eur J Pain Section Abstract Doc Link 17466547 Disease Relevance 0.69 Pain Relevance 0.59
The effects of Tityus serrulatus venom and of two of its toxic fractions, toxin gamma (Tx gamma) and T2III1, on the rat isolated diaphragm were examined. 2.
Regulation (effects) of Tx gamma in diaphragm
3) Confidence 0.04 Published 1989 Journal Gen. Pharmacol. Section Abstract Doc Link 2714618 Disease Relevance 0 Pain Relevance 0.06
In this study we assessed the effect of a TxA2 synthase inhibitor, Dazmegrel, and a TxA2 receptor antagonist, SQ-29 548, on glomerular PGE2, LTB4, and 12-HETE synthesis in a model of mesangial nephritis induced in the rat by the administration of a monoclonal antibody against the Thy 1.1 antigen of rat mesangial cells.
Regulation (effect) of TxA2 in mesangial cells associated with nephritis and antagonist
4) Confidence 0.01 Published 1999 Journal J. Lab. Clin. Med. Section Abstract Doc Link 10560941 Disease Relevance 0.56 Pain Relevance 0.22

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