INT280701

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (gr)
Anatomy Link Frequency
nucleus 3
gr (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 140 78.80 Quite High
tolerance 12 9.80 Low Low
Glutamate 8 5.00 Very Low Very Low Very Low
spastic colon 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 24.72 Low Low
Insulin Resistance 8 14.64 Low Low
Exsanguination 8 5.00 Very Low Very Low Very Low
Diabetes Mellitus 8 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 4 5.00 Very Low Very Low Very Low
Organ Transplantation 4 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Muscle Weakness 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The estimated degradation rate constant for GR mRNA was very similar to previously reported values based on data from Quantitative Northern Hybridization measurements (Sun et al. 1998a; Sun et al. 1998b).
Protein_catabolism (degradation) of GR
1) Confidence 0.03 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.07
where symbols represent cytosolic free plasma MPL (CMPL,f) where the unbound fraction of MPL was fixed to 0.23 (Kong and Jusko, 1991), free glucocorticoid receptor density (R), GR mRNA (mRNAGR), cytosolic GR-drug complex (DR), GR-drug complex in nucleus (DR(N)), zero-order GR mRNA synthesis rate constant (ksyn,GRmRNA), and first-order rate constants for GR mRNA degradation (kdgr,GRmRNA), GR synthesis (ksyn,GR) and GR degradation (kdgr,GR).
Protein_catabolism (degradation) of GR in nucleus
2) Confidence 0.03 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.04
where symbols represent cytosolic free plasma MPL (CMPL,f) where the unbound fraction of MPL was fixed to 0.23 (Kong and Jusko, 1991), free glucocorticoid receptor density (R), GR mRNA (mRNAGR), cytosolic GR-drug complex (DR), GR-drug complex in nucleus (DR(N)), zero-order GR mRNA synthesis rate constant (ksyn,GRmRNA), and first-order rate constants for GR mRNA degradation (kdgr,GRmRNA), GR synthesis (ksyn,GR) and GR degradation (kdgr,GR).
Protein_catabolism (degradation) of GR in nucleus
3) Confidence 0.03 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.04
where symbols represent cytosolic free plasma MPL (CMPL,f) where the unbound fraction of MPL was fixed to 0.23 (Kong and Jusko, 1991), free glucocorticoid receptor density (R), GR mRNA (mRNAGR), cytosolic GR-drug complex (DR), GR-drug complex in nucleus (DR(N)), zero-order GR mRNA synthesis rate constant (ksyn,GRmRNA), and first-order rate constants for GR mRNA degradation (kdgr,GRmRNA), GR synthesis (ksyn,GR) and GR degradation (kdgr,GR).
Protein_catabolism (degradation) of GR in nucleus
4) Confidence 0.02 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.03

General Comments

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