INT280786

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Aqp2) plasma membrane (Aqp2) protein complex (Aqp2)
transmembrane transport (Aqp2) lysosome (Aqp2) cytoplasm (Aqp2)
Anatomy Link Frequency
vesicles 1
Aqp2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 26 5.00 Very Low Very Low Very Low
Kinase C 24 5.00 Very Low Very Low Very Low
Neuropeptide 18 5.00 Very Low Very Low Very Low
dexamethasone 18 5.00 Very Low Very Low Very Low
amygdala 16 5.00 Very Low Very Low Very Low
medulla 8 5.00 Very Low Very Low Very Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 56 82.08 Quite High
Pressure Volume 2 Under Development 4 78.40 Quite High
Hypertension 2 41.36 Quite Low
Shock 2 35.52 Quite Low
Emergencies 2 34.48 Quite Low
Polyuria 2 27.16 Quite Low
Diabetes Insipidus 2 26.08 Quite Low
Aggression 2 14.32 Low Low
Targeted Disruption 20 5.00 Very Low Very Low Very Low
Hyponatremia 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, AQP2 is dephosphorylated and internalized to the original stores in the cytoplasm.
Phosphorylation (dephosphorylated) of AQP2
1) Confidence 0.32 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.24 Pain Relevance 0
Afterwards, a water channel, aquaporine2 (AQP2), which is present in the intracellular vesicles, is rapidly phosphorylated at the portion of Ser256 through the cAMP/PKA-dependent pathway (Fushimi et al. 1993; Kuwahara et al. 1995).
Phosphorylation (phosphorylated) of AQP2 in vesicles
2) Confidence 0.32 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0 Pain Relevance 0

General Comments

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