INT280794

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Aqp2) plasma membrane (Aqp2) protein complex (Aqp2)
transmembrane transport (Aqp2) lysosome (Aqp2) cytoplasm (Aqp2)
Anatomy Link Frequency
plasma 1
vesicles 1
Aqp2 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 17 5.00 Very Low Very Low Very Low
cytokine 13 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
medulla 10 5.00 Very Low Very Low Very Low
depression 10 5.00 Very Low Very Low Very Low
amygdala 9 5.00 Very Low Very Low Very Low
Neuropeptide 9 5.00 Very Low Very Low Very Low
dexamethasone 9 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 108 73.92 Quite High
Pressure Volume 2 Under Development 2 41.28 Quite Low
Targeted Disruption 70 37.76 Quite Low
Polyuria 1 27.16 Quite Low
Diabetes Insipidus 1 26.08 Quite Low
Aggression 18 5.00 Very Low Very Low Very Low
Depression 12 5.00 Very Low Very Low Very Low
Anxiety Disorder 12 5.00 Very Low Very Low Very Low
Sprains And Strains 12 5.00 Very Low Very Low Very Low
Hypoglycemia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Afterwards, a water channel, aquaporine2 (AQP2), which is present in the intracellular vesicles, is rapidly phosphorylated at the portion of Ser256 through the cAMP/PKA-dependent pathway (Fushimi et al. 1993; Kuwahara et al. 1995).
Localization (present) of AQP2 in vesicles
1) Confidence 0.36 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0 Pain Relevance 0
The renal Avpr2 is responsible for water resorption in kidney collecting ducts by promoting the translocation of aquaporin-2 channels to the plasma membrane (Knepper 1997).
Localization (translocation) of aquaporin-2 in plasma
2) Confidence 0.08 Published 2011 Journal Stress (Amsterdam, Netherlands) Section Body Doc Link PMC3016603 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.

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