INT280820

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (S100a8, Crh) extracellular region (S100a8, Crh) cytoplasm (S100a8, Crh)
plasma membrane (S100a8) cytoskeleton (S100a8) response to stress (Crh)
Anatomy Link Frequency
neurons 2
S100a8 (Mus musculus)
Crh (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 3 100.00 Very High Very High Very High
cytokine 13 99.96 Very High Very High Very High
medulla 4 42.08 Quite Low
Pain 1 17.04 Low Low
Kinase C 12 5.00 Very Low Very Low Very Low
Neuropeptide 9 5.00 Very Low Very Low Very Low
dexamethasone 9 5.00 Very Low Very Low Very Low
amygdala 8 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 100.00 Very High Very High Very High
Adrenal Insufficiency 2 81.52 Quite High
Syndrome 1 76.32 Quite High
Hyponatremia 5 71.44 Quite High
Frailty 2 69.88 Quite High
Stress 28 67.00 Quite High
Targeted Disruption 10 65.84 Quite High
Hypoglycemia 2 62.72 Quite High
Meningitis 1 48.80 Quite Low
Viral Meningitis 1 47.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of the vasopressin and CRH gene in the PVN parvocellular neurons is induced by the pro-inflammatory cytokines.
pro-inflammatory Positive_regulation (induced) of Gene_expression (expression) of CRH gene in neurons associated with inflammation and cytokine
1) Confidence 0.01 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.65 Pain Relevance 0.19

General Comments

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