INT280823

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkaca, Crh) mitochondrion (Prkaca) Golgi apparatus (Prkaca)
protein complex (Prkaca) response to stress (Crh) extracellular space (Crh)
Prkaca (Mus musculus)
Crh (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 9 11.96 Low Low
depression 2 8.80 Low Low
cytokine 13 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
dexamethasone 9 5.00 Very Low Very Low Very Low
amygdala 8 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 2 54.48 Quite High
Reprotox - General 1 1 52.40 Quite High
Eating Disorder 1 9.68 Low Low
Depression 2 8.80 Low Low
Pituitary Acth Hypersecretion 1 8.32 Low Low
Hyponatremia 5 6.48 Low Low
Stress 28 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activation of the PKA signaling also increases the CRH gene expression in rat fetal hypothalamic cultures (Emanuel et al. 1992), or primary amygdalar cultures (Kasckow et al. 1997).
Positive_regulation (activation) of PKA Positive_regulation (increases) of Gene_expression (expression) of CRH gene
1) Confidence 0.08 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.11 Pain Relevance 0

General Comments

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