INT280826

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, Avp) extracellular region (Il6, Avp) signal transduction (Avp)
signal transducer activity (Avp)
Il6 (Mus musculus)
Avp (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 26 100.00 Very High Very High Very High
Kinase C 24 75.84 Quite High
Inflammation 6 75.76 Quite High
Central nervous system 4 40.88 Quite Low
Neurotransmitter 4 37.60 Quite Low
Neuropeptide 18 5.00 Very Low Very Low Very Low
dexamethasone 18 5.00 Very Low Very Low Very Low
amygdala 16 5.00 Very Low Very Low Very Low
medulla 8 5.00 Very Low Very Low Very Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 4 82.80 Quite High
INFLAMMATION 8 75.76 Quite High
Hyponatremia 10 73.76 Quite High
Viral Meningitis 2 72.92 Quite High
Meningitis 2 72.28 Quite High
Stress 56 72.24 Quite High
Volume Depletion And Dehydration 4 70.88 Quite High
Syndrome 2 58.44 Quite High
Adrenal Insufficiency 4 23.40 Low Low
Frailty 4 11.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors confirmed the coexistence of vasopressin and IL-6 in SON of the dehydrated rat, suggesting that IL-6 promotes the induction of the vasopressin expression and/or secretion through the autocrine/paracrine system.
IL-6 Positive_regulation (promotes) of Localization (secretion) of vasopressin
1) Confidence 0.01 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.34 Pain Relevance 0.09
, IL-6 and other cytokines can promote the induction of the transcription and/or secretion of CRH/vasopressin in vivo.
IL-6 Positive_regulation (promote) of Localization (secretion) of vasopressin associated with cytokine
2) Confidence 0.01 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.30 Pain Relevance 0.38

General Comments

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