INT280828

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Avp, Avpr2) signal transducer activity (Avp, Avpr2) extracellular space (Avp)
extracellular region (Avp) plasma membrane (Avpr2)
Avp (Mus musculus)
Avpr2 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 51 5.00 Very Low Very Low Very Low
agonist 27 5.00 Very Low Very Low Very Low
depression 26 5.00 Very Low Very Low Very Low
medulla 22 5.00 Very Low Very Low Very Low
Hippocampus 14 5.00 Very Low Very Low Very Low
cytokine 13 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
amygdala 11 5.00 Very Low Very Low Very Low
Neuropeptide 9 5.00 Very Low Very Low Very Low
Catecholamine 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 268 96.72 Very High Very High Very High
Pressure Volume 2 Under Development 2 35.92 Quite Low
Polyuria 1 30.52 Quite Low
Diabetes Insipidus 1 29.44 Quite Low
Targeted Disruption 190 5.00 Very Low Very Low Very Low
Aggression 52 5.00 Very Low Very Low Very Low
Sprains And Strains 36 5.00 Very Low Very Low Very Low
Depression 32 5.00 Very Low Very Low Very Low
Anxiety Disorder 28 5.00 Very Low Very Low Very Low
Hypoglycemia 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Arginine vasopressin (Avp) is a cyclic nonapeptide that exerts diverse biological effects through a number of receptors (R), three of which have been cloned to date in mammals; the vasopressin Avprla, Avprlb and Avpr2—Avp also binds to the structurally related oxytocin (Oxt) receptor (Oxtr) with high affinity.
vasopressin Binding (binds) of Avpr2
1) Confidence 0.15 Published 2011 Journal Stress (Amsterdam, Netherlands) Section Body Doc Link PMC3016603 Disease Relevance 0.09 Pain Relevance 0
Arginine vasopressin (Avp) is a cyclic nonapeptide that exerts diverse biological effects through a number of receptors (R), three of which have been cloned to date in mammals; the vasopressin Avprla, Avprlb and Avpr2—Avp also binds to the structurally related oxytocin (Oxt) receptor (Oxtr) with high affinity.
Avp Binding (binds) of Avpr2
2) Confidence 0.15 Published 2011 Journal Stress (Amsterdam, Netherlands) Section Body Doc Link PMC3016603 Disease Relevance 0.10 Pain Relevance 0
Arginine vasopressin (Avp) is a cyclic nonapeptide that exerts diverse biological effects through a number of receptors (R), three of which have been cloned to date in mammals; the vasopressin Avprla, Avprlb and Avpr2—Avp also binds to the structurally related oxytocin (Oxt) receptor (Oxtr) with high affinity.
vasopressin Binding (binds) of Avpr2
3) Confidence 0.13 Published 2011 Journal Stress (Amsterdam, Netherlands) Section Body Doc Link PMC3016603 Disease Relevance 0.10 Pain Relevance 0
A rapid accumulation of the intracellular cAMP and the subsequent activation of protein kinase A (PKA) is observed, after vasopressin in the circulation binds V2R.
vasopressin Binding (binds) of V2R
4) Confidence 0.01 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0 Pain Relevance 0

General Comments

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