INT280839

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, Crh) extracellular region (Il6, Crh) response to stress (Crh)
cytoplasm (Crh)
Il6 (Mus musculus)
Crh (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 12 90.88 High High
cytokine 13 72.16 Quite High
Inflammation 3 40.56 Quite Low
Central nervous system 2 5.68 Low Low
Neuropeptide 9 5.00 Very Low Very Low Very Low
dexamethasone 9 5.00 Very Low Very Low Very Low
amygdala 8 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 2 97.84 Very High Very High Very High
INFLAMMATION 4 40.56 Quite Low
Stress 28 37.04 Quite Low
Volume Depletion And Dehydration 2 35.68 Quite Low
Hyponatremia 5 29.84 Quite Low
Viral Meningitis 1 29.00 Quite Low
Meningitis 1 28.36 Quite Low
Syndrome 1 14.52 Low Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, IL-6 also increases the CRH gene expression in hypothalamic explants (Lyson and McCann, 1993), dissociated amygdalar cultures (Kasckow et al. 1997), and human endometrial cells (Makrigiannakis et al. 1999).
IL-6 Positive_regulation (increases) of Gene_expression (expression) of CRH gene
1) Confidence 0.09 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.10 Pain Relevance 0.19

General Comments

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