INT280850

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Crh, Ucn, Crh) extracellular space (Crh, Crh) response to stress (Crh, Crh)
cytoplasm (Crh, Crh)
Crh (Mus musculus)
Ucn (Mus musculus)
Crh (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 3 88.80 High High
amygdala 8 85.44 High High
medulla 4 84.64 Quite High
Hippocampus 2 76.96 Quite High
Spinal cord 2 31.00 Quite Low
Thalamus 1 28.64 Quite Low
Limbic system 1 26.88 Quite Low
cytokine 13 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
Neuropeptide 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 10 57.76 Quite High
Stress 28 41.68 Quite Low
Diabetes Insipidus 1 9.60 Low Low
Polyuria 1 6.00 Low Low
Hyponatremia 5 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Small Cell Lung Cancer 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the systemic circulation, CRH and Ucn1 are known to bind CRH-binding protein (CRH-BP), resulting in the inactivation of CRH and Ucn1 (Potter et al. 1991).
CRH-binding protein Binding (bind) of Ucn1 Positive_regulation (resulting) of Negative_regulation (inactivation) of CRH
1) Confidence 0.26 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.06 Pain Relevance 0.27

General Comments

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