INT280862

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Msn) nucleolus (Msn) plasma membrane (Msn)
cytoskeleton (Msn) nucleus (Msn) protein binding, bridging (Msn)
Anatomy Link Frequency
neuronal 2
Msn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
potassium channel 3 99.12 Very High Very High Very High
Neuronal excitability 2 97.76 Very High Very High Very High
repetitive firing 1 96.72 Very High Very High Very High
Dopamine 93 69.24 Quite High
Action potential 13 48.72 Quite Low
Enkephalin 4 5.00 Very Low Very Low Very Low
Nucleus accumbens 4 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
dopamine receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 5 5.00 Very Low Very Low Very Low
Decapitation 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Respiratory Tract Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesized that this increase in MSN intrinsic excitability could involve A-type potassium channels, which control neuronal excitability and repetitive firing [25].
Positive_regulation (increase) of Localization (excitability) of MSN in neuronal associated with neuronal excitability, repetitive firing and potassium channel
1) Confidence 0.35 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2733153 Disease Relevance 0 Pain Relevance 0.30

General Comments

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