INT280863

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Context Info
Confidence 0.62
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Msn) nucleolus (Msn) plasma membrane (Msn)
cytoskeleton (Msn) nucleus (Msn) protein binding, bridging (Msn)
Msn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 93 99.52 Very High Very High Very High
potassium channel 3 28.92 Quite Low
Neuronal excitability 2 22.92 Low Low
Action potential 13 5.00 Very Low Very Low Very Low
Enkephalin 4 5.00 Very Low Very Low Very Low
Nucleus accumbens 4 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
dopamine receptor 2 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 5 5.00 Very Low Very Low Very Low
Decapitation 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Respiratory Tract Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Altogether, this strongly suggests that the decrease in IA leads to the observed increase in intrinsic excitability of MSN in case of dopamine depletion.


Protein_catabolism (excitability) of MSN associated with dopamine
1) Confidence 0.62 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2733153 Disease Relevance 0 Pain Relevance 0.35

General Comments

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