INT280894

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Context Info
Confidence 0.38
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk1) plasma membrane (Ntrk1) nucleus (Runx1)
DNA binding (Runx1) kinase activity (Ntrk1) transcription factor binding (Runx1)
Runx1 (Mus musculus)
Ntrk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 5 74.72 Quite High
dorsal root ganglion 24 66.80 Quite High
Peripheral nervous system 1 25.44 Quite Low
nociceptor 8 17.76 Low Low
Spinal cord 6 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 90.40 High High
Death 1 76.40 Quite High
Neurodegenerative Disease 2 70.72 Quite High
Ganglion Cysts 24 66.80 Quite High
Nociception 9 57.84 Quite High
Neurological Disease 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the chick, it has been suggested that Runx1 directly activates TrkA transcription and that Runx1 overexpression in progenitors in vivo induces ectopic expression of TrkA [32].
Runx1 Positive_regulation (activates) of Transcription (transcription) of TrkA
1) Confidence 0.38 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0.36 Pain Relevance 0.07

General Comments

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