INT280895

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Context Info
Confidence 0.33
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ret) nucleus (Runx1) DNA binding (Runx1)
kinase activity (Ret) transcription factor binding (Runx1)
Runx1 (Mus musculus)
Ret (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 5 98.16 Very High Very High Very High
TRP channel 1 97.20 Very High Very High Very High
Kinase C 1 94.08 High High
Glutamate receptor 1 92.32 High High
nociceptor 87 72.72 Quite High
Pain 17 63.92 Quite High
Inflammation 14 50.00 Quite Low
Neuropeptide 1 44.24 Quite Low
sodium channel 1 32.64 Quite Low
nav1.8 2 32.04 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 18 78.80 Quite High
Pain 20 63.92 Quite High
INFLAMMATION 14 50.00 Quite Low
Ganglion Cysts 24 25.44 Quite Low
Neuropathic Pain 44 5.00 Very Low Very Low Very Low
Inflammatory Pain 19 5.00 Very Low Very Low Very Low
Nociception 9 5.00 Very Low Very Low Very Low
Hyperalgesia 7 5.00 Very Low Very Low Very Low
Nervous System Injury 6 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We reported previously that Runx1 is partially required for the expression of Ret and the ATP-gated channel P2X3 [14].
Runx1 Positive_regulation (required) of Gene_expression (expression) of Ret
1) Confidence 0.33 Published 2010 Journal Mol Pain Section Body Doc Link PMC2919460 Disease Relevance 0.20 Pain Relevance 0.33
In collaboration with the Runx1-induced ectopic expression of the growth factor receptors TrkA and RET, these extrinsic factors may significantly contribute to survival and possibly also to differentiation of the DOX-treated, transplanted bNCSCs.
Runx1 Positive_regulation (induced) of Gene_expression (expression) of RET
2) Confidence 0.30 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0 Pain Relevance 0.25

General Comments

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