INT280940

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.28
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Inhbe)
Anatomy Link Frequency
neurons 1
microglial cells 1
Inhbe (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 28 100.00 Very High Very High Very High
Inflammation 150 99.04 Very High Very High Very High
Central nervous system 42 98.88 Very High Very High Very High
fibrosis 2 97.52 Very High Very High Very High
Inflammatory response 20 93.40 High High
cINOD 52 80.96 Quite High
antagonist 16 68.20 Quite High
Hippocampus 70 5.00 Very Low Very Low Very Low
Intracerebroventricular 8 5.00 Very Low Very Low Very Low
Pyramidal cell 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 178 99.04 Very High Very High Very High
Fibrosis 2 97.52 Very High Very High Very High
Neurodegenerative Disease 256 88.08 High High
Cancer 6 85.68 High High
Necrosis 6 85.20 High High
Hepatocellular Cancer 2 83.52 Quite High
Gliosis 46 48.12 Quite Low
Disease 14 19.44 Low Low
Injury 20 5.00 Very Low Very Low Very Low
Hypertrophy 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our study shows that activin A, which is released by neurons, is an anti-inflammatory agent in the CNS.
Localization (released) of activin in neurons associated with inflammation and central nervous system
1) Confidence 0.07 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 1.03 Pain Relevance 0.67
Since we observed changes in microglial morphology, we next set out to determine whether activin A altered cytokine release from microglial cells.
Localization (release) of activin in microglial cells associated with cytokine
2) Confidence 0.07 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 0.26 Pain Relevance 0.17

General Comments

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