INT280944

Context Info Confidence 0.22 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.91 Pain Relevance 0.31

peptidase activity (Bmp1) extracellular space (Bmp1)

Bmp1 (Mus musculus)

Pain Link Frequency Relevance Heat Central nervous system 21 99.68 cytokine 14 93.64 Inflammation 75 93.24 antagonist 8 85.28 cINOD 26 59.44 Inflammatory response 10 35.76 fibrosis 1 26.48 Hippocampus 35 5.00 Intracerebroventricular 4 5.00 Pyramidal cell 2 5.00

Disease Link Frequency Relevance Heat Neurodegenerative Disease 128 97.48 INFLAMMATION 89 93.24 Gliosis 23 89.52 Fibrosis 1 26.48 Injury 10 5.00 Disease 7 5.00 Hypertrophy 4 5.00 Death 4 5.00 Necrosis 3 5.00 Cancer 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

superfamily ligands such as BMP1, BMP2, BMP5, and BMP7 were also expressed in the CNS after KA-induced neurodegeneration (supporting information Table 1).

Gene_expression (expressed) of BMP1 associated with central nervous system

1) Confidence 0.22 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 0.91 Pain Relevance 0.31

General Comments

This test has worked.