INT280946

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 1.36
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sema5b)
Anatomy Link Frequency
spikes 1
neurons 1
paw 1
Sema5b (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 6 96.58 Very High Very High Very High
allodynia 11 95.12 Very High Very High Very High
Dorsal horn 12 91.32 High High
Spinal cord 28 81.60 Quite High
Cold hyperalgesia 7 77.04 Quite High
Hippocampus 111 76.84 Quite High
antagonist 26 67.44 Quite High
withdrawal 15 60.40 Quite High
Hyperalgesia 17 50.00 Quite Low
Thermal hyperalgesia 12 45.28 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 35 95.12 Very High Very High Very High
Aids-related Complex 132 85.88 High High
Nociception 49 84.12 Quite High
Hyperalgesia 37 77.04 Quite High
Targeted Disruption 39 69.88 Quite High
Cancer 13 66.00 Quite High
Necrosis 9 65.52 Quite High
Injury 33 62.24 Quite High
Neurodegenerative Disease 384 56.68 Quite High
INFLAMMATION 282 34.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
cells with the most transient responses were indistinguishable from those of the Opn1mwR “transient” population at either wavelength (Figure 5C; mean ± SEM increases over baseline 0–2 s after light on; 2.3±0.4, 3.1±0.6, and 2.5±0.4 spikes/s, respectively; one-way ANOVA with Bonferroni post-test, all p>0.05).
Positive_regulation (increases) of SEM in spikes
1) Confidence 0.05 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2998442 Disease Relevance 0 Pain Relevance 0
Three separate trials were carried out on three separate days at base line and two separate trials during and after drug treatment at weeks 1, 3, 6, and 8 were averaged and presented as the mean number of paw lifts ± SEM.


Positive_regulation (lifts) of SEM in paw
2) Confidence 0.05 Published 2010 Journal Mol Pain Section Body Doc Link PMC2848188 Disease Relevance 0.17 Pain Relevance 0.23
A single subcutaneous injection of capsaicin resulted in the lowest average number of labeled neurons per section (2.6 ± 0.6 SEM, n = 6), while wrapping the paw in a gauze soaked with 25% mustard oil (MO) for 2 hrs induced the highest number of neurons (50 ± 3.5 SEM, n = 5).
Positive_regulation (induced) of SEM in neurons associated with qutenza
3) Confidence 0.04 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 0.94 Pain Relevance 0.26
Values are mean ± SEM. ?
Positive_regulation (mean) of SEM
4) Confidence 0.02 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 0.13 Pain Relevance 0
Values for all graphs are mean ± SEM. ?
Positive_regulation (mean) of SEM
5) Confidence 0.02 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 0 Pain Relevance 0.03
Values for all graphs are mean ± SEM. ?
Positive_regulation (mean) of SEM
6) Confidence 0.02 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733378 Disease Relevance 0.12 Pain Relevance 0.06

General Comments

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