INT28097

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Context Info
Confidence 0.11
First Reported 1989
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 4.07
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
WBC 4
lung 1
neutrophils 1
Wbc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 1 97.20 Very High Very High Very High
cva 1 96.32 Very High Very High Very High
shoulder pain 1 91.16 High High
Arthritis 1 90.36 High High
headache 11 82.32 Quite High
cINOD 1 75.00 Quite High
Pain 3 29.20 Quite Low
Inflammation 11 14.04 Low Low
Bioavailability 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disseminated Intravascular Coagulation 3 99.80 Very High Very High Very High
Leukopenia 3 98.36 Very High Very High Very High
Appetite Loss 1 97.72 Very High Very High Very High
Depression 1 97.20 Very High Very High Very High
Dyspnea 1 96.72 Very High Very High Very High
Lung Cancer 2 96.32 Very High Very High Very High
Cv General 3 Under Development 1 96.32 Very High Very High Very High
Cough 1 95.68 Very High Very High Very High
Congenital Anomalies 12 95.64 Very High Very High Very High
Body Weight 2 94.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The white blood cell (WBC) count was 8,200/?
Negative_regulation (white blood cell) of WBC in white blood cell
1) Confidence 0.11 Published 1994 Journal Infect Dis Obstet Gynecol Section Abstract Doc Link PMC2364358 Disease Relevance 0.87 Pain Relevance 0.14
When WBC decreased to less than or equal to 3,000/mm3 after the 1st course of chemotherapy, 131 patients with lung cancer, who were previously classified by the combination regimens of chemotherapy, were enrolled in the study and randomized into 3 groups, 200 micrograms (H), 100 micrograms (L) and untreated control (C) groups.
Negative_regulation (decreased) of WBC in lung associated with lung cancer
2) Confidence 0.09 Published 1989 Journal Arzneimittelforschung Section Abstract Doc Link 2719748 Disease Relevance 0.34 Pain Relevance 0
A slow decrease in white blood cell (WBC) count, the number of neutrophils, MID (mixed number of monocytes, eosinophils and basophils) and in the individual number of monocytes (CD14/CD45 positive cells) was observed in Groups I and III.
Negative_regulation (decrease) of WBC in neutrophils
3) Confidence 0.01 Published 2003 Journal Vet. Microbiol. Section Abstract Doc Link 14516708 Disease Relevance 0.95 Pain Relevance 0.12
In phase 1, one subject receiving 100 mg of FM-VP4 showed a decrease in WBC count 24 h after treatment, but this was considered unrelated to the study drug and returned to normal 7 days after treatment.
Negative_regulation (decrease) of WBC
4) Confidence 0.01 Published 2008 Journal Eur J Clin Pharmacol Section Body Doc Link PMC2426926 Disease Relevance 0.50 Pain Relevance 0.16
One subject who received 100 mg of FM-VP4 showed a decrease in white blood cell (WBC) count from 6.2?
Negative_regulation (decrease) of WBC in WBC
5) Confidence 0.01 Published 2008 Journal Eur J Clin Pharmacol Section Body Doc Link PMC2426926 Disease Relevance 0.13 Pain Relevance 0
The patient was treated with enocitabine, daunorubicin, 6-mercaptopurine, dalteparin sodium, anti-thrombin III concentrates and gabexate mesilate with prophylactic frozen transfusions of fresh plasma and platelet transfusions for 5 days, but WBC count did not decrease and DIC did not improve.
Neg (not) Negative_regulation (decrease) of WBC in WBC associated with disseminated intravascular coagulation
6) Confidence 0.01 Published 1996 Journal Rinsho Ketsueki Section Abstract Doc Link 8997125 Disease Relevance 1.10 Pain Relevance 0.11
Significant decline in WBC, DLC, and PCV was also noticed.
Negative_regulation (decline) of WBC
7) Confidence 0.01 Published 2010 Journal Toxicology International Section Abstract Doc Link PMC2964740 Disease Relevance 0.18 Pain Relevance 0
Circulating white blood cell (WBC) counts were decreased in septic wild-type mice compared with sham-operated controls (0.9 ± 0.1 × 106 cells/ml versus 1.7 ± 0.2 × 106 cells/ml; P < 0.05).
Negative_regulation (decreased) of WBC in white blood cell
8) Confidence 0.00 Published 2007 Journal Crit Care Section Body Doc Link PMC2246221 Disease Relevance 0 Pain Relevance 0

General Comments

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