INT281038

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serping1) extracellular region (Serping1) molecular_function (Serping1)
cellular_component (Serping1) biological_process (Serping1)
Serping1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bradykinin 6 33.84 Quite Low
headache 2 18.88 Low Low
Potency 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hereditary Angioedema 82 99.84 Very High Very High Very High
Infection 38 99.84 Very High Very High Very High
Hepatitis 12 97.68 Very High Very High Very High
Hepatitis B Virus Infection 38 96.64 Very High Very High Very High
Hepatitis C Virus Infection 28 94.80 High High
Pressure And Volume Under Development 22 90.16 High High
Communicable Diseases 4 87.24 High High
Viral Infection 2 86.60 High High
Ulcers 4 77.56 Quite High
Disease 12 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immune complexes of these viruses may affect the CP of complement, leading to a further reduction in C1-INH in HAE patients.
Positive_regulation (leading) of Negative_regulation (reduction) of C1-INH associated with hereditary angioedema
1) Confidence 0.10 Published 2008 Journal Arch Immunol Ther Exp (Warsz) Section Body Doc Link PMC2734250 Disease Relevance 1.27 Pain Relevance 0
Therefore the second objective of this study was to investigate whether exacerbations of acute HAE could be initiated by stimulation of the immune response by infectious agents, leading to complement activation and depletion of C1-INH.
Positive_regulation (leading) of Negative_regulation (depletion) of C1-INH associated with hereditary angioedema
2) Confidence 0.08 Published 2008 Journal Arch Immunol Ther Exp (Warsz) Section Body Doc Link PMC2734250 Disease Relevance 1.36 Pain Relevance 0

General Comments

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