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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cxcr4) aging (Ccl2) signal transducer activity (Cxcr4)
cytoplasm (Ccl2) extracellular space (Ccl2) extracellular region (Ccl2)
Ccl2 (Rattus norvegicus)
Cxcr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 2 91.68 High High
dorsal root ganglion 42 88.76 High High
chemokine 52 66.56 Quite High
cytokine 3 54.24 Quite High
Inflammatory response 2 49.84 Quite Low
c fibre 2 48.32 Quite Low
nociceptor 5 47.68 Quite Low
Thermal hyperalgesia 3 26.84 Quite Low
Neuropathic pain 12 25.28 Quite Low
Sciatic nerve 6 20.80 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 91.68 High High
Ganglion Cysts 42 88.76 High High
Rheumatoid Arthritis 10 80.40 Quite High
Injury 33 76.68 Quite High
Nociception 7 60.32 Quite High
Nervous System Injury 8 59.28 Quite High
Neuropathic Pain 16 57.20 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 21 50.00 Quite Low
Hyperalgesia 5 26.84 Quite Low
Demyelinating Disease 3 19.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hence, the importance of MCP1/CCR2 signaling following administration of a T-tropic gp120/hCD4 may involve a hierarchy of effects wherein initial interactions with CXCR4 lead to downstream changes in MCP1/CCR2 functional signaling.
MCP1 Binding (interactions) of CXCR4
1) Confidence 0.06 Published 2009 Journal Mol Pain Section Body Doc Link PMC2734548 Disease Relevance 0.63 Pain Relevance 0.24

General Comments

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