INT281241

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (P2rx3) plasma membrane (P2RX7) cytoplasm (P2RX7)
P2RX7 (Homo sapiens)
P2rx3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropathic pain 1 97.16 Very High Very High Very High
Inflammation 1 96.32 Very High Very High Very High
antagonist 1 93.88 High High
Analgesic 1 91.72 High High
Pain 19 91.20 High High
agonist 4 74.24 Quite High
ischemia 1 35.12 Quite Low
Lasting pain 2 5.00 Very Low Very Low Very Low
bradykinin 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 1 97.16 Very High Very High Very High
INFLAMMATION 2 96.32 Very High Very High Very High
Pain 22 91.20 High High
Male Infertility 1 54.24 Quite High
Death 2 53.20 Quite High
Nociception 1 51.60 Quite High
Diabetes Mellitus 1 50.28 Quite High
Hypertension 2 49.68 Quite Low
Demyelinating Disease 1 48.92 Quite Low
Disease 1 45.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, this picture is complicated by a recent report showing P2X7 receptor activation down-regulated the expression of P2X3 in DRGs [85].
Positive_regulation (activation) of P2X7 receptor Negative_regulation (regulated) of Gene_expression (expression) of P2X3
1) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2735677 Disease Relevance 0.79 Pain Relevance 0.71

General Comments

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