INT281280

Context Info Confidence 0.41 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.52 Pain Relevance 0.06

cell differentiation (Stx2)

Anatomy Link Frequency monocyte 2 Stx2 (Mus musculus)

Pain Link Frequency Relevance Heat agonist 18 63.36 Inflammation 6 5.00 cytokine 4 5.00 withdrawal 2 5.00 Crohn's disease 2 5.00 Angina 2 5.00

Disease Link Frequency Relevance Heat Stress 14 91.84 Hemolytic Uremic Syndrome 82 86.16 Thrombotic Microangiopathies 6 56.16 Sepsis 6 54.52 Cv Unclassified Under Development 2 50.60 Endotoxemia 8 47.16 Acute Coronary Syndrome 2 44.88 Thrombosis 2 39.52 Injury 6 28.40 Disease 12 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Co-stimulation with Stx2 and LPS resulted in an additive effect with regard to platelet-monocyte aggregate formation and TF expression on these aggregates, particularly when high shear forces were applied.

Positive_regulation (resulted) of Positive_regulation (stimulation) of Stx2 in monocyte

1) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2735777 Disease Relevance 0.52 Pain Relevance 0

Stx2 and EHEC-LPS induce tissue factor–positive microparticles

Positive_regulation (microparticles) of Positive_regulation (induce) of Stx2

2) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2735777 Disease Relevance 0 Pain Relevance 0.06

General Comments

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