INT281308

Context Info Confidence 0.06 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4) cytoplasm (Tlr4)

Anatomy Link Frequency neutrophil 1 tf (Mus musculus) Tlr4 (Mus musculus)

Pain Link Frequency Relevance Heat agonist 9 5.00 Inflammation 3 5.00 cytokine 2 5.00 withdrawal 1 5.00 Crohn's disease 1 5.00 Angina 1 5.00

Disease Link Frequency Relevance Heat Heart Rate Under Development 5 23.32 Hemolytic Uremic Syndrome 41 5.00 Stress 7 5.00 Disease 6 5.00 Acute Renal Failure 5 5.00 Endotoxemia 4 5.00 Thrombocytopenia 3 5.00 Thrombotic Microangiopathies 3 5.00 Sepsis 3 5.00 Injury 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

LPS induced increased platelet-neutrophil aggregates with surface-bound TF, whereas Stx only had a negligible effect (Figure 4B).

TF Binding (bound) of LPS in neutrophil

1) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2735777 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.