INT281380

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) protein binding, bridging (FSCN1) DNA binding (Fos)
cytoplasm (FSCN1) response to stress (Fos) cell proliferation (FSCN1)
Anatomy Link Frequency
dorsal horn 2
Fos (Rattus norvegicus)
FSCN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal nerve ligature 57 100.00 Very High Very High Very High
allodynia 36 99.96 Very High Very High Very High
Dorsal horn 12 99.20 Very High Very High Very High
spinal dorsal horn 9 29.84 Quite Low
intrathecal 7 6.72 Low Low
Neuropathic pain 24 5.00 Very Low Very Low Very Low
Pain 17 5.00 Very Low Very Low Very Low
Spinal cord 5 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 61 99.96 Very High Very High Very High
Nociception 16 87.96 High High
Injury 3 86.44 High High
Nervous System Injury 16 66.80 Quite High
Pain 17 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Besides its effect on the SNL-induced ipsilateral mechanic allodynia, c-fos ASO significantly inhibited SNL-induced Fos protein expression in the ipsilateral dorsal horn.
c-fos ASO Negative_regulation (inhibited) of Gene_expression (expression) of SNL-induced in dorsal horn associated with allodynia, spinal nerve ligature and dorsal horn
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736402 Disease Relevance 0.40 Pain Relevance 0.96

General Comments

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