INT281382

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (FSCN1, Sds) cell proliferation (FSCN1) mitochondrion (Sds)
lyase activity (Sds) cell motility (FSCN1) protein binding, bridging (FSCN1)
Anatomy Link Frequency
astrocytes 1
FSCN1 (Homo sapiens)
Sds (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal nerve ligature 57 100.00 Very High Very High Very High
allodynia 36 100.00 Very High Very High Very High
spinal dorsal horn 9 100.00 Very High Very High Very High
Pain 17 94.08 High High
Neuropathic pain 24 92.80 High High
intrathecal 7 86.56 High High
Dorsal horn 12 5.00 Very Low Very Low Very Low
Spinal cord 5 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 61 100.00 Very High Very High Very High
Pain 17 94.08 High High
Nervous System Injury 16 80.00 Quite High
Nociception 16 31.04 Quite Low
Injury 3 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SNL induced a significant mechanical allodynia as well as activated SDH neurons indicated by the Fos expression at the early phase and activated astrocytes with the increased expression of GFAP during the late phase of pain, respectively.
SNL Positive_regulation (activated) of SDH in astrocytes associated with pain, allodynia, spinal dorsal horn and spinal nerve ligature
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2736402 Disease Relevance 0.84 Pain Relevance 1.33

General Comments

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