INT281466

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Context Info
Confidence 0.33
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Akt1) aging (Akt1) enzyme binding (Akt1)
carbohydrate metabolic process (Akt1) cytoplasm (Akt1) cytosol (Akt1)
Anatomy Link Frequency
dopamine neurons 2
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 115 99.68 Very High Very High Very High
Nicotine 1 96.20 Very High Very High Very High
Serotonin 3 88.72 High High
Glutamate 1 82.44 Quite High
Substantia nigra 8 62.64 Quite High
midbrain 15 55.60 Quite High
Hippocampus 1 42.08 Quite Low
cerebral cortex 1 41.44 Quite Low
Ventral tegmentum 8 5.00 Very Low Very Low Very Low
Eae 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 1 96.24 Very High Very High Very High
Targeted Disruption 6 83.76 Quite High
Death 9 65.56 Quite High
Apoptosis 10 65.12 Quite High
Congenital Anomalies 1 45.28 Quite Low
Hypertrophy 3 44.20 Quite Low
Macrocephaly 2 43.08 Quite Low
Glioblastoma 2 6.64 Low Low
Cancer 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These studies suggest PTEN function in dopamine neurons is not limited to the classical deregulation of the Akt pathway, and PTEN may also have an effect on distinct functions related to dopamine-mediated cognition.
Neg (not) Negative_regulation (limited) of Regulation (deregulation) of Akt in dopamine neurons associated with cognitive disorder and dopamine
1) Confidence 0.33 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736587 Disease Relevance 0.31 Pain Relevance 0.63

General Comments

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