INT281472

Context Info Confidence 0.03 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.45

unfolded protein binding (St13) protein folding (St13) cytosol (St13) protein complex (St13) cytoplasm (St13)

Anatomy Link Frequency neurons 2 St13 (Mus musculus)

Pain Link Frequency Relevance Heat Dopamine 115 91.96 Eae 7 75.00 5HT 1 64.64 midbrain 15 58.04 Catecholamine 1 56.88 Dynorphin 6 11.44 Enkephalin 2 10.88 Ventral tegmentum 8 5.00 Substantia nigra 8 5.00 monoamine 3 5.00

Disease Link Frequency Relevance Heat Apoptosis 10 5.00 Death 9 5.00 Cancer 7 5.00 Targeted Disruption 6 5.00 Disease 5 5.00 Hypertrophy 3 5.00 Macrocephaly 2 5.00 Glioblastoma 2 5.00 Overdose 1 5.00 Toxicity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Four weeks after the lesion, control 6OHDA-treated mice showed an extensive loss of TH positive SNc neurons in the ipsilateral or lesioned nigral region (Fig. 8A and B).

Negative_regulation (loss) of Positive_regulation (neurons) of SNc in neurons

1) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736587 Disease Relevance 0 Pain Relevance 0.45

General Comments

This test has worked.