INT281586

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Context Info
Confidence 0.47
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Trim63) intracellular (Trim63) ligase activity (Trim63)
cytoplasm (Trim63)
Anatomy Link Frequency
myocardium 1
Trim63 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 3 40.32 Quite Low
analgesia 1 5.00 Very Low Very Low Very Low
nalbuphine 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscular Atrophy 1 55.12 Quite High
Sepsis 3 37.08 Quite Low
Myocardial Infarction 2 32.28 Quite Low
Heart Rate Under Development 5 5.00 Very Low Very Low Very Low
Coronary Heart Disease 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is feasible that this is in part a consequence of the failure of the myocardium to elicit events typically associated with UP-mediated protein degradation, most notably MAFbx/atrogin-1 and MuRF1 mRNA elevation.
Protein_catabolism (degradation) of MuRF1 mRNA in myocardium
1) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736646 Disease Relevance 0.06 Pain Relevance 0

General Comments

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