INT281595

Context Info Confidence 0.33 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.32 Pain Relevance 0.05

nucleus (Trim63) intracellular (Trim63) ligase activity (Trim63) cytoplasm (Trim63)

Trim63 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Spinal cord 1 91.44 cytokine 3 44.16 analgesia 1 5.00 nalbuphine 1 5.00

Disease Link Frequency Relevance Heat Myocardial Infarction 2 87.36 Coronary Heart Disease 1 74.08 Heart Rate Under Development 5 50.48 Sepsis 3 50.40 Muscular Atrophy 1 14.96 Necrosis 1 5.00 Cancer 1 5.00 Pressure Volume 2 Under Development 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It is possible therefore that myocardial contraction could be responsible for the maintenance of MAFbx/atrogin-1 and MuRF1 mRNA at basal levels.

Regulation (responsible) of MuRF1 mRNA Binding (maintenance) of

1) Confidence 0.33 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736646 Disease Relevance 0.32 Pain Relevance 0.05

General Comments

This test has worked.