INT281600

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Casq1) Golgi apparatus (Casq1) molecular_function (Casq1)
response to stress (Casq1) cytoplasm (Casq1)
Anatomy Link Frequency
cardiomyocytes 1
skeletal muscle 1
Casq1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
nalbuphine 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 52 99.84 Very High Very High Very High
Myocardial Infarction 6 58.56 Quite High
Apoptosis 25 53.48 Quite High
Lymphatic System Cancer 1 42.32 Quite Low
B-cell Acute Lymphoblastic Leukemia 1 41.96 Quite Low
Injury 16 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Heart Rate Under Development 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Sepsis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, mRNA levels of Na+-Ca2+ exchanger (NCX) and calsequestrin increased in hypoxia-reoxygenated cardiomyocytes.
Positive_regulation (increased) of calsequestrin in cardiomyocytes associated with hypoxia
1) Confidence 0.05 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.66 Pain Relevance 0
Consistent with our previously reported findings [3], we observed 24 h LPS administration to result in reduced fast-twitch skeletal muscle protein content, elevated mRNA levels of MAFbx/atrogin-1 and MuRF1, and an increase in protein levels for multiple subunits of the 20S proteasome; observations that are in accordance with the reported rise in UP-mediated protein degradation during endotoxaemia in fast-twitch muscle [32].
Positive_regulation (elevated) of fast-twitch in skeletal muscle
2) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736646 Disease Relevance 0 Pain Relevance 0

General Comments

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