INT281617

Context Info Confidence 0.44 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0

FBXO32 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 6 5.00 analgesia 2 5.00 nalbuphine 2 5.00 Spinal cord 2 5.00

Disease Link Frequency Relevance Heat Heart Rate Under Development 10 5.00 Sepsis 6 5.00 Myocardial Infarction 4 5.00 Coronary Heart Disease 2 5.00 Muscular Atrophy 2 5.00 Necrosis 2 5.00 Cancer 2 5.00 Pressure Volume 2 Under Development 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

At the same time point, a significant increase in MAFbx/atrogin-1 and MuRF1 mRNA (3.7±0.7- and 19.5±1.9-fold increase vs. controls, respectively; P<0.05), in addition to protein levels of ?

Regulation (0.7) of Positive_regulation (increase) of MAFbx

1) Confidence 0.44 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2736646 Disease Relevance 0 Pain Relevance 0

At the same time point, a significant increase in MAFbx/atrogin-1 and MuRF1 mRNA (3.7±0.7- and 19.5±1.9-fold increase vs. controls, respectively; P<0.05), in addition to protein levels of ?

Regulation (0.7) of Positive_regulation (increase) of atrogin-1

2) Confidence 0.44 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2736646 Disease Relevance 0 Pain Relevance 0

General Comments

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