INT281623

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Cdk2ap1 (Mus musculus)
Pain Link Frequency Relevance Heat
endometriosis 6 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Taxol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 98.86 Very High Very High Very High
Cancer 154 98.20 Very High Very High Very High
Colon Cancer 98 91.32 High High
Apoptosis 1 63.36 Quite High
Microsatellite Instability 41 49.72 Quite Low
Malignant Neoplastic Disease 5 35.92 Quite Low
Polyps 19 24.24 Low Low
Hereditary Nonpolyposis Colorectal Neoplasms 61 17.84 Low Low
Familial Adenomatous Polyposis 46 5.00 Very Low Very Low Very Low
Adenoma 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All four of the GI tumors harvested from the Mlh1 knockout mouse exhibited the MSI phenotype and had significantly decreased levels of CDK2-AP1 mRNA (p < 0.0001) and protein.
Negative_regulation (decreased) of Transcription (levels) of CDK2-AP1 associated with targeted disruption and cancer
1) Confidence 0.01 Published 2007 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2736982 Disease Relevance 1.62 Pain Relevance 0

General Comments

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