INT281659

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Context Info
Confidence 0.27
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.12
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (HMOX1) endoplasmic reticulum (HMOX1) enzyme binding (HMOX1)
transmembrane transport (HMOX1) signal transducer activity (HMOX1) cytosol (HMOX1)
HMOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 7 98.48 Very High Very High Very High
ischemia 36 97.36 Very High Very High Very High
Inflammation 30 92.88 High High
Inflammatory marker 1 82.56 Quite High
cva 7 70.96 Quite High
Inflammatory response 10 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 30 97.36 Very High Very High Very High
INFLAMMATION 40 92.88 High High
Increased Venous Pressure Under Development 5 91.60 High High
Hypoxia 4 88.16 High High
Stress 10 86.52 High High
Vasculitis 2 83.48 Quite High
Hyperplasia 1 82.28 Quite High
Coronary Artery Disease 11 80.80 Quite High
Apoptosis 14 80.00 Quite High
Atherosclerosis 8 78.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that the (GT)n repeat is highly polymorphic and modulates the transcriptional activity of HO-1 gene [23,24].
Regulation (modulates) of Transcription (activity) of HO-1 gene
1) Confidence 0.27 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2841098 Disease Relevance 1.37 Pain Relevance 0.08
In contrast, local mRNA expression of HO-1 was unaltered by IR (Table 2).


Regulation (unaltered) of Transcription (expression) of HO-1
2) Confidence 0.15 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2737143 Disease Relevance 0.75 Pain Relevance 0.25

General Comments

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