INT28173

Context Info Confidence 0.73 First Reported 1989 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 8 Total Number 8 Disease Relevance 3.40 Pain Relevance 1.83

nucleus (DBP)

Anatomy Link Frequency urine 1 DBP (Homo sapiens)

Pain Link Frequency Relevance Heat Analgesic 2 98.84 Multiple sclerosis 59 98.72 tolerance 2 97.76 nalbuphine 4 97.24 Pain 18 94.52 Perioperative pain 1 89.52 intrathecal 1 61.40 Pain threshold 2 54.24 Inflammation 35 52.32 cytokine 3 52.00

Disease Link Frequency Relevance Heat Obesity 26 99.28 Demyelinating Disease 60 98.72 Clinical Trials And Case Reports 4 98.32 Hypertension 130 95.48 Pressure And Volume Under Development 8 94.64 Pain 19 94.52 Disease 30 92.48 Increased Venous Pressure Under Development 14 87.16 Nicotine Addiction 9 84.88 Stress 35 84.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In both groups SBP, DBP and RR decreased and HR increased significantly after injection but the tolerance of nalbuphine seems to be beter.

Localization (decreased) of DBP associated with nalbuphine and tolerance

1) Confidence 0.73 Published 1989 Journal Acta Anaesthesiol Belg Section Abstract Doc Link 2728834 Disease Relevance 0.17 Pain Relevance 0.90

These results indicate that excretion of urinary DBP is increased after long-term Cd exposure and that the loss of DBP in urine may be linked to renal tubular dysfunction and possibly bone lesions in the inhabitants of Cd-polluted areas.

Localization (excretion) of DBP in urine

2) Confidence 0.65 Published 2007 Journal Tohoku J. Exp. Med. Section Abstract Doc Link 17347552 Disease Relevance 0.38 Pain Relevance 0.06

The QAlb values indicate lack of CSF-barrier dysfunction in MS subjects included in our study, and it is very likely that the depletion of GSN and DBP from CSF that occurs as these proteins bind actin cannot be compensated for by an increased production or transport of gelsolin.

Localization (depletion) of DBP associated with multiple sclerosis

3) Confidence 0.64 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2989318 Disease Relevance 0.49 Pain Relevance 0.24

The present study demonstrated that green odor attenuated the increase in SBP and DBP induced by CPT and facilitated recovery of Ts without having any effect on these parameters, under non-stressful conditions.

Localization (increase) of DBP

4) Confidence 0.53 Published 2008 Journal Biopsychosoc Med Section Body Doc Link PMC2259378 Disease Relevance 0.64 Pain Relevance 0.64

Normalization of DBP was observed in some patients on 300 mg and 400 mg after 7 days of treatment.

Localization (Normalization) of DBP

5) Confidence 0.43 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717814 Disease Relevance 0.08 Pain Relevance 0

The meta analysis showed that in five studies with the combination versus placebo, the between-group weighted mean differences (WMDs) for both SBP and DBP favored perindopril plus indapamide (SBP ?

Localization (weighted) of DBP associated with clinical trials and case reports

6) Confidence 0.32 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012553 Disease Relevance 0.41 Pain Relevance 0

Aside from sex, the strongest predictor of both SBP and DBP among Tsimane is BMI (standardized estimate?

Localization (predictor) of DBP associated with obesity

7) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722089 Disease Relevance 0.95 Pain Relevance 0

Moreover, SBP increases abruptly to a value more than DBP, i.e., pulse pressure increases.11,13,20 Data collection and analysis

Localization (more) of DBP

8) Confidence 0.25 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2852789 Disease Relevance 0.27 Pain Relevance 0

General Comments

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