INT28176

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Context Info
Confidence 0.73
First Reported 1988
Last Reported 2011
Negated 1
Speculated 3
Reported most in Abstract
Documents 17
Total Number 20
Disease Relevance 14.30
Pain Relevance 4.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cp) oxidoreductase activity (Cp) aging (Cp)
extracellular region (Cp)
Anatomy Link Frequency
reservoir 2
blood 1
retina 1
parenchyma 1
Cp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 34 100.00 Very High Very High Very High
Angina 4 99.44 Very High Very High Very High
alcohol 4 99.36 Very High Very High Very High
Inflammation 78 98.00 Very High Very High Very High
Prostatitis 33 92.42 High High
nud 2 92.24 High High
Arthritis 54 84.56 Quite High
cINOD 1 82.24 Quite High
Pain 3 79.08 Quite High
antagonist 2 77.44 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 53 100.00 Very High Very High Very High
Adenocarcinoma 16 100.00 Very High Very High Very High
Hypertension 1 99.84 Very High Very High Very High
Stress 9 99.54 Very High Very High Very High
Cv General 3 Under Development 4 99.44 Very High Very High Very High
Ulcers 3 99.44 Very High Very High Very High
Gastritis 9 99.36 Very High Very High Very High
Duodenal Ulcer 6 99.32 Very High Very High Very High
Nicotine Addiction 4 99.28 Very High Very High Very High
INFLAMMATION 79 98.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therapy studies so far using either bismuth, antibiotics, or a combination of both could demonstrate that the healing of DU ulcer was closely related to the clearance of Cp and healing of gastritis.
Localization (clearance) of Cp associated with ulcers, duodenal ulcer and gastritis
1) Confidence 0.73 Published 1988 Journal Scand. J. Gastroenterol. Suppl. Section Abstract Doc Link 3047854 Disease Relevance 1.59 Pain Relevance 0.07
Long-Evans Cinnamon (LEC) rats inherently lacking in serum ceruloplasmin (CP) activity and biliary Cu excretion were established from a closed colony of Long-Evans rats.
Localization (excretion) of CP
2) Confidence 0.69 Published 2000 Journal Arch. Toxicol. Section Abstract Doc Link 10959791 Disease Relevance 0 Pain Relevance 0.11
Long-Evans Cinnamon (LEC) rats inherently lacking in serum ceruloplasmin (CP) activity and biliary Cu excretion were established from a closed colony of Long-Evans rats.
Localization (excretion) of ceruloplasmin
3) Confidence 0.69 Published 2000 Journal Arch. Toxicol. Section Abstract Doc Link 10959791 Disease Relevance 0 Pain Relevance 0.11
Thus cardiac of CP and ICD patients should be used to a large extend for the recovery of individual physical and psychological integrity as well as for the organisation of reemployment.
Localization (cardiac) of CP
4) Confidence 0.61 Published 2010 Journal Dtsch. Med. Wochenschr. Section Abstract Doc Link 20373274 Disease Relevance 0.30 Pain Relevance 0.07
The return to work rate of CP and ICD patients is resumably influenced by the underlying cardiac disease and to a lesser extend by the implanted device.
Localization (rate) of CP associated with heart disease
5) Confidence 0.57 Published 2010 Journal Dtsch. Med. Wochenschr. Section Abstract Doc Link 20373274 Disease Relevance 0.40 Pain Relevance 0.08
Ductal changes, including distortion, dilatation, and pancreatic ductal hypertension in the setting of CP, induce genomic damage and increased cell turnover.
Localization (setting) of CP associated with hypertension and chronic pancreatitis
6) Confidence 0.56 Published 2009 Journal Lab. Invest. Section Abstract Doc Link 19308045 Disease Relevance 1.49 Pain Relevance 0.52
A 4-yr follow-up study of symptoms, endoscopic appearance, and histologic findings including the presence of CP was performed in 10 of the original 16 patients.
Localization (presence) of CP
7) Confidence 0.40 Published 1989 Journal Am. J. Gastroenterol. Section Abstract Doc Link 2729235 Disease Relevance 0.74 Pain Relevance 0.13
Of particular interest for future studies are those proteins that are not normalized (Fgf2 and Crybb2) or only partially normalized (Cp, Cryba3, Lgals3, Stat3) by insulin treatment, as these persistent changes reflect the limitations of insulin to restore the retina to a nondiabetic state.
Neg (not) Localization (normalized) of Cp in retina
8) Confidence 0.31 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020973 Disease Relevance 0.17 Pain Relevance 0
The etiology of RAP and CP is complex, and effects of alcohol and smoking may be limited to specific patient subsets.
Localization (etiology) of CP associated with nicotine addiction, pancreatitis, chronic pancreatitis and alcohol
9) Confidence 0.26 Published 2009 Journal Arch. Intern. Med. Section Abstract Doc Link 19506173 Disease Relevance 0.93 Pain Relevance 0.64
Serum ceruloplasmin is a good surrogate marker of copper status because the liver secretes this copper-containing protein into the blood at a rate dependent on copper availability [40].
Localization (secretes) of ceruloplasmin in blood
10) Confidence 0.23 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297562 Disease Relevance 0.85 Pain Relevance 0.26
BACKGROUND: We investigated the time course and prognostic value of fibrinogen (Fib), C-reactive protein (CRP), interleukin-6 (IL-6), and ceruloplasmin (CP) in patients with severe unstable angina.
Spec (investigated) Localization (value) of CP associated with angina
11) Confidence 0.22 Published 2009 Journal Angiology Section Abstract Doc Link 18388036 Disease Relevance 0.17 Pain Relevance 0.17
BACKGROUND: We investigated the time course and prognostic value of fibrinogen (Fib), C-reactive protein (CRP), interleukin-6 (IL-6), and ceruloplasmin (CP) in patients with severe unstable angina.
Spec (investigated) Localization (value) of ceruloplasmin associated with angina
12) Confidence 0.22 Published 2009 Journal Angiology Section Abstract Doc Link 18388036 Disease Relevance 0.17 Pain Relevance 0.17
Since the etiology of nonbacterial prostatitis has not yet been established, various factors have been reported, including Trichomonas vaginalis, Chlamydia trachomatis, genital mycoplasmas, Staphylococci, Coryneforms, genital viruses, biofilm, stagnation of prostatic secretion, autoimmune diseases, allergy, sex hormone disorders, and psychological factors.21-23 In the present study, oxidative stress was investigated as a cause of CP.
Spec (investigated) Localization (cause) of CP associated with stress, autoimmune disease, hypersensitivity, prostatitis and chlamydia infection
13) Confidence 0.19 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2703763 Disease Relevance 1.58 Pain Relevance 0.49
The CP was a totally implanted port, had Dacron anchoring cuffs with a reservoir and a single lumen, and was used for both inpatients and outpatients.
Localization (used) of CP in reservoir
14) Confidence 0.18 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2995228 Disease Relevance 0.51 Pain Relevance 0
The CP was a totally implanted port, had Dacron anchoring cuffs with a reservoir and a single lumen, and was used for both inpatients and outpatients.
Localization (port) of CP in reservoir
15) Confidence 0.18 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2995228 Disease Relevance 0.43 Pain Relevance 0
Although the precise localization of PGDH (epithelial and/or stromal) within the CP is unclear (see infra), the latter observation suggests that the metabolism capacity of the tissue towards PGE2 is lower than its uptake capacity.
Localization (localization) of CP
16) Confidence 0.12 Published 2008 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC2292143 Disease Relevance 0 Pain Relevance 0
Endocrine endowment reduction, noted by a lower percent of chromogranin + pancreatic parenchyma, was seen in AIP (4.54%) and CP (3.20%) compared to NP (7.95%); only the CP decrease was statistically significant (P = 0.02) since AIP often had ductular endocrine neogenesis.
Localization (decrease) of CP in parenchyma associated with pancreatitis and chronic pancreatitis
17) Confidence 0.07 Published 2010 Journal Virchows Arch. Section Abstract Doc Link 20632032 Disease Relevance 1.80 Pain Relevance 0.63
CP is a risk factor for PDAC, CP is found within the vicinity of PDAC, and both share many similar genetic alterations.
Localization (found) of CP associated with adenocarcinoma and chronic pancreatitis
18) Confidence 0.04 Published 2009 Journal Clin. Gastroenterol. Hepatol. Section Abstract Doc Link 19896097 Disease Relevance 1.58 Pain Relevance 0.63
CP is a risk factor for PDAC, CP is found within the vicinity of PDAC, and both share many similar genetic alterations.
Localization (found) of CP associated with adenocarcinoma and chronic pancreatitis
19) Confidence 0.04 Published 2009 Journal Clin. Gastroenterol. Hepatol. Section Abstract Doc Link 19896097 Disease Relevance 1.58 Pain Relevance 0.64
The luminescence quenching is proportional to the concentration of aPase and CP within the range of 0.1-70 mU mL(-1) and 0.3-20 microg mL(-1), respectively.
Localization (concentration) of CP
20) Confidence 0.03 Published 2008 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 18596346 Disease Relevance 0 Pain Relevance 0.14

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