INT281814

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Akt1) aging (Akt1) enzyme binding (Akt1)
carbohydrate metabolic process (Akt1) cytoplasm (Akt1) cytosol (Akt1)
Akt1 (Mus musculus)
Phgdh (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 34 100.00 Very High Very High Very High
Cancer 94 93.92 High High
Apoptosis 3 71.40 Quite High
Pancreatic Cancer 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Glioblastoma 1 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Solid Tumor 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DCA is a pyruvate-mimetic that can increase pyruvate dehyrogenase activity in hypoxic cells by inhibiting pyruvate dehydrogenase kinases [31].
Negative_regulation (inhibiting) of kinases Positive_regulation (increase) of dehyrogenase associated with hypoxia
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2737639 Disease Relevance 1.70 Pain Relevance 0

General Comments

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