INT28185

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Context Info
Confidence 0.29
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RYBP) small molecule metabolic process (CYP2B6) endoplasmic reticulum (CYP2B6)
nucleus (RYBP) intracellular (RYBP) DNA binding (RYBP)
Anatomy Link Frequency
liver 2
CYP2B6 (Homo sapiens)
RYBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 17 100.00 Very High Very High Very High
alcohol 1 33.96 Quite Low
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Toxicity 1 49.52 Quite Low
Necrosis 1 33.60 Quite Low
Hepatotoxicity 2 27.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of the other purified P450 isozymes examined, a beta-naphthoflavone (BNF)-inducible hamster liver P450 promoted APAP activation at rates even higher than those obtained with human P450IIE1.
P450 Positive_regulation (promoted) of Positive_regulation (activation) of APAP in liver associated with paracetamol
1) Confidence 0.29 Published 1989 Journal Arch. Biochem. Biophys. Section Abstract Doc Link 2729995 Disease Relevance 0 Pain Relevance 0.82

General Comments

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