INT28186

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Context Info
Confidence 0.04
First Reported 1989
Last Reported 1989
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RYBP) small molecule metabolic process (CYP2E1) oxidoreductase activity (CYP2E1)
endoplasmic reticulum (CYP2E1) nucleus (RYBP) intracellular (RYBP)
Anatomy Link Frequency
liver 2
CYP2E1 (Homo sapiens)
RYBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 17 100.00 Very High Very High Very High
alcohol 1 83.32 Quite High
Analgesic 1 69.68 Quite High
Disease Link Frequency Relevance Heat
Toxicity 1 98.88 Very High Very High Very High
Necrosis 1 82.96 Quite High
Hepatotoxicity 2 76.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We therefore examined the role of P450IIE1 in human liver microsomal APAP activation.
P450IIE1 Spec (examined) Regulation (role) of Spec (examined) Positive_regulation (activation) of APAP in liver associated with paracetamol
1) Confidence 0.04 Published 1989 Journal Arch. Biochem. Biophys. Section Abstract Doc Link 2729995 Disease Relevance 0.33 Pain Relevance 1.08

General Comments

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