INT281868

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.69
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Park7) mitochondrion organization (Park7) response to stress (Park7)
cytoplasm (Park7) cytosol (Park7) peptidase activity (Park7)
Anatomy Link Frequency
neuronal 1
Park7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 1 99.00 Very High Very High Very High
midbrain 18 64.48 Quite High
addiction 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 11 100.00 Very High Very High Very High
Toxicity 4 100.00 Very High Very High Very High
Alzheimer's Dementia 1 99.38 Very High Very High Very High
Cv General 4 Under Development 1 99.00 Very High Very High Very High
Aging 1 98.52 Very High Very High Very High
Stress 12 97.80 Very High Very High Very High
Epilepsy 1 89.44 High High
Ataxia 1 88.32 High High
Supranuclear Palsy 1 87.48 High High
Disease 9 86.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, aconitase inactivation has been observed in various animal and cell models of neuronal disorders and oxidative stress [32], [33] including excitotoxicity [17], cerebral ischemia [34], beta-amyloid toxicity [35], oxygen-glucose deprivation [30], MPTP toxicity [16], Sod2 and DJ1 mutant mice [18], [36], [37] as well as in aging [38], [39].
Negative_regulation (deprivation) of DJ1 mutant in neuronal associated with parkinson's disease, stress, toxicity, aging, cv general 4 under development, ischemia and alzheimer's dementia
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2738973 Disease Relevance 1.69 Pain Relevance 0.14

General Comments

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