INT281872
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Oxidative inactivation of m-aconitase leads to cell death | |||||||||||||||
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Our data demonstrate that oxidative inactivation of m-aconitase results in the formation of Fenton reactants in neuronal cells which provides evidence for the pathogenic mechanism in which m-aconitase not only serves as a target but also as a source of oxidants. | |||||||||||||||
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Oxidative inactivation of overexpressed m-aconitase exacerbates H2O2 production and mitochondrial iron accumulation | |||||||||||||||
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General Comments
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