INT281881

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.93
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) mitochondrion (Aco1) lyase activity (Aco1)
Golgi apparatus (Aco1) endoplasmic reticulum (Aco1) cytoplasm (Aco1)
Aco1 (Mus musculus)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 2 93.52 High High
midbrain 36 60.00 Quite High
addiction 2 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 2 99.48 Very High Very High Very High
Toxicity 8 96.76 Very High Very High Very High
Parkinson's Disease 22 96.40 Very High Very High Very High
Alzheimer's Dementia 2 94.28 High High
Cv General 4 Under Development 2 93.52 High High
Stress 24 92.76 High High
Neurodegenerative Disease 8 91.72 High High
Epilepsy 2 84.96 Quite High
Ataxia 2 83.84 Quite High
Supranuclear Palsy 2 83.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aconitase has been well established as a sensitive target of ROS; however the consequences of oxidative inactivation of this important enzyme still remain to be fully understood.
Aconitase Binding (target) of ROS
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2738973 Disease Relevance 0.33 Pain Relevance 0
Aconitase has been widely recognized as a sensitive and relatively specific target of ROS, particularly O2.?.
Aconitase Binding (recognized) of ROS
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2738973 Disease Relevance 1.60 Pain Relevance 0.10

General Comments

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