INT281931

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Context Info
Confidence 0.69
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.57
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ACE2) extracellular space (ACE2) extracellular region (ACE2)
plasma membrane (ACE2)
Anatomy Link Frequency
uterine 1
ACE2 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 2 68.64 Quite High
antagonist 8 19.64 Low Low
ischemia 36 8.80 Low Low
bradykinin 11 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-eclampsia 33 99.68 Very High Very High Very High
Systemic Lupus Erythematosus 48 96.32 Very High Very High Very High
Necrosis 14 94.72 High High
Ganglion Cysts 2 69.36 Quite High
Amputation 2 61.12 Quite High
Cv Unclassified Under Development 36 8.80 Low Low
Pulmonary Hypertension 62 7.52 Low Low
Disease 60 5.00 Very Low Very Low Very Low
Systemic Sclerosis 56 5.00 Very Low Very Low Very Low
Hypertension 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in Figure 3d, the ACE2 levels in Patients 1 and 5, who were deficient in ACE2 activity (Figure 3c), were comparable with those in three healthy subjects, clearly indicating that the decreased ACE2 activity in the vasculopathy patients was due to a functional deficiency.
Transcription (activity) of ACE2
1) Confidence 0.69 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911869 Disease Relevance 0.14 Pain Relevance 0
Recovery of serum ACE2 activity after therapy in one patient
Transcription (activity) of ACE2
2) Confidence 0.69 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911869 Disease Relevance 0.32 Pain Relevance 0.07
In rats submitted to a reduction of uterine perfusion pressure (RUPP), a model that mimics preeclampsia, the placental expression of Ang-(1–7) and ACE2 mRNA is decreased[90].
Transcription (expression) of ACE2 in uterine associated with pre-eclampsia
3) Confidence 0.49 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2739214 Disease Relevance 0.10 Pain Relevance 0

General Comments

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